Cardiovascular diseases (CVDs), particularly ischemic heart disease (IHD) and stroke, present epidemiologically in a different way among sexes.The reasons of these sex-based differences should be delved into sex-specific cardiovascular (CV) risk factors and different mechanisms of atherosclerotic progression.Imaging techniques of both carotid and coronary atherosclerotic plaques baltimore a minuit represent a tool to demonstrate sex-related features which might be used to further and better assess CV risk of male and female population.The aim of this review is to evaluate current knowledge on sex-specific qualitative and goveda juha quantitative plaque features of coronary and carotid atherosclerosis.We also discuss the clinical implication of a sex-based plaque phenotype, evaluated with non-invasive imaging techniques, such as CT-angiography and MRI-angiography, to stratify CV risk.